![Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091, @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected NSCLC. The study did meet its primary endpoint (DFS HR Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091, @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected NSCLC. The study did meet its primary endpoint (DFS HR](https://pbs.twimg.com/media/FUlZ6kiWQAEN4xK.jpg)
Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091, @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected NSCLC. The study did meet its primary endpoint (DFS HR
![KEYTRUDA® (pembrolizumab) Showed Statistically Significant Improvement In Disease-Free Survival Versus Placebo As Adjuvant Treatment For Patients With Stage IB-IIIA Non-Small Cell Lung Cancer Regardless Of PD-L1 Expression 2023 - EORTC KEYTRUDA® (pembrolizumab) Showed Statistically Significant Improvement In Disease-Free Survival Versus Placebo As Adjuvant Treatment For Patients With Stage IB-IIIA Non-Small Cell Lung Cancer Regardless Of PD-L1 Expression 2023 - EORTC](http://www.eortc.org/app/uploads/2022/01/Press-release-Merck-.png)
KEYTRUDA® (pembrolizumab) Showed Statistically Significant Improvement In Disease-Free Survival Versus Placebo As Adjuvant Treatment For Patients With Stage IB-IIIA Non-Small Cell Lung Cancer Regardless Of PD-L1 Expression 2023 - EORTC
![IJMS | Free Full-Text | Targeted Therapy and Immunotherapy in Early-Stage Non-Small Cell Lung Cancer: Current Evidence and Ongoing Trials IJMS | Free Full-Text | Targeted Therapy and Immunotherapy in Early-Stage Non-Small Cell Lung Cancer: Current Evidence and Ongoing Trials](https://www.mdpi.com/ijms/ijms-23-07222/article_deploy/html/images/ijms-23-07222-g001.png)
IJMS | Free Full-Text | Targeted Therapy and Immunotherapy in Early-Stage Non-Small Cell Lung Cancer: Current Evidence and Ongoing Trials
![Gaining an Advantage Over NSCLC: How to Achieve the Greatest Benefit With Immunotherapy From Advanced to Gaining an Advantage Over NSCLC: How to Achieve the Greatest Benefit With Immunotherapy From Advanced to](https://image.slidesharecdn.com/pvislidesharergk-220630145923-d06501fa/85/gaining-an-advantage-over-nsclc-how-to-achieve-the-greatest-benefit-with-immunotherapy-from-advanced-to-early-disease-36-320.jpg?cb=1669798143)
Gaining an Advantage Over NSCLC: How to Achieve the Greatest Benefit With Immunotherapy From Advanced to
![Aɴᴛᴏɴɪᴏ Pᴀssᴀʀᴏ on Twitter: "🚨 Adjuvant pembrolizumab for early-stage NSCLC following complete resection: the ph III PEARLS(KEYNOTE-091) by Luis Paz Ares @ETOP_eu @EORTC #LCSM Primary endpoint: DSF in overall population and PDL1 Aɴᴛᴏɴɪᴏ Pᴀssᴀʀᴏ on Twitter: "🚨 Adjuvant pembrolizumab for early-stage NSCLC following complete resection: the ph III PEARLS(KEYNOTE-091) by Luis Paz Ares @ETOP_eu @EORTC #LCSM Primary endpoint: DSF in overall population and PDL1](https://pbs.twimg.com/media/FOEqp00X0Aoh4ll.jpg)
Aɴᴛᴏɴɪᴏ Pᴀssᴀʀᴏ on Twitter: "🚨 Adjuvant pembrolizumab for early-stage NSCLC following complete resection: the ph III PEARLS(KEYNOTE-091) by Luis Paz Ares @ETOP_eu @EORTC #LCSM Primary endpoint: DSF in overall population and PDL1
![Stephen V Liu, MD on Twitter: "#ASCO22 While PEARLS did meet its endpoint, we already have atezolizumab approved in this space after IMpower 010. Notes differences between these trials and again - Stephen V Liu, MD on Twitter: "#ASCO22 While PEARLS did meet its endpoint, we already have atezolizumab approved in this space after IMpower 010. Notes differences between these trials and again -](https://pbs.twimg.com/media/FUlag_kXsAIgfg5.jpg)
Stephen V Liu, MD on Twitter: "#ASCO22 While PEARLS did meet its endpoint, we already have atezolizumab approved in this space after IMpower 010. Notes differences between these trials and again -
![Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology](https://www.thelancet.com/cms/attachment/ec7c3133-ee63-42d7-aa87-9abb68be5221/gr1.gif)
Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology
![Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology](https://www.thelancet.com/cms/attachment/34067555-57dc-411d-93d4-2cb1d2c6dfba/gr3_lrg.jpg)
Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology
![Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial | AIOM Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial | AIOM](https://www.aiom.it/wp-content/uploads/2022/10/Lancet-Oncology_Oct22._In-Evidenza.jpg)
Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial | AIOM
![Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091, @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected NSCLC. The study did meet its primary endpoint (DFS HR Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091, @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected NSCLC. The study did meet its primary endpoint (DFS HR](https://pbs.twimg.com/media/FUlZ0RmWIAkNt2M.jpg)
Stephen V Liu, MD on Twitter: "#ASCO22 Discussion of PEARLS (KEYNOTE-091, @ETOP_eu 8-15), a phase III study of adjuvant pembrolizumab in resected NSCLC. The study did meet its primary endpoint (DFS HR
![KEYNOTE-091 - Adjuvant Therapy for Stage 1B (T2a ≥4 cm), Stage 2, or Stage 3A NSCLC Clinical Trial Results KEYNOTE-091 - Adjuvant Therapy for Stage 1B (T2a ≥4 cm), Stage 2, or Stage 3A NSCLC Clinical Trial Results](https://www.keytrudahcp.com/static/211ab844f86484296c428df62acbe774/af158/nsclc-adjuvant-KM-DFS091-v6.png)
KEYNOTE-091 - Adjuvant Therapy for Stage 1B (T2a ≥4 cm), Stage 2, or Stage 3A NSCLC Clinical Trial Results
PharmaShots. - • The P-III (KEYNOTE-091/EORTC-1416-LCG/ETOP-8-15 – PEARLS) trial evaluates Keytruda (200mg, IV, q3w) for 1yr. vs PBO in a ratio (1:1) in 1177 patients with stage IB to IIIA NSCLC following
Frühes nichtkleinzelliges Bronchialkarzinom: Pembrolizumab adjuvant nach Resektion verlängert das krankheitsfreie Überleben
![Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial - The Lancet Oncology](https://www.thelancet.com/cms/attachment/736216f9-9797-4861-84cb-44eb96590de6/gr2_lrg.jpg)